While many men feel significantly better on TRT, some may experience side effects, especially in the early stages of treatment. Common side effects include:
- Increased red blood cell count (polycythemia)
- Acne or oily skin
- Fluid retention
- Mood changes, including increased irritability
- Breast tissue growth (gynecomastia) in rare cases
- Testicular shrinkage due to suppressed natural testosterone production
- Testicular shrinkage due to suppressed natural testosterone production
If you notice side effects, don’t panic—many are manageable with adjustments:
- Work with your doctor to adjust your dose or switch delivery methods (injections, gels, etc.).
- Monitor blood markers regularly to ensure your treatment remains safe.
- Lifestyle changes like diet, hydration, and exercise can help manage certain side effects.